Publications
Mechanisms and Pathophysiology of SARS-CoV-2 infection of the adipose tissue. J. Moser, M. Emous, P. Heeringa, I.A. Rodenhuis-Zybert. Trends in Endocrinology and Metabolism , Sept 2023, https://doi.org/10.1016/j.tem.2023.08.010
Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study. C. den Uil, F. Termorshuizen, W. Rietdijk, R.S. Sablerolles, H.P.M. van der Kuy, L.E.M. Haas, P.H.J. van der Voort, D. de Lange, P. Pickkers, N.F. de Keizer, the Dutch COVID-19 Research Consortium. Crit Care Med, Feb 2023, DOI: 10.1097/CCM.0000000000005788.
Circulating adipokine levels and COVID-19 severity in hospitalized patients.
A.W. Flikweert, A.C. Muller Kobold, S. van der Sar-van der Brugge, P Heeringa, I.A. Rodenhuis-Zybert, J Bijzet, A Tami, B.T.F. van der Gun, K.I. Wold, A. Huckriede, H. Franke, J.M.A. Emmen, M Emous, M.J.J.H. Grootenboers, M van Meurs, P.H.J. van der Voort, J. Moser. International Journal of Obesity, Dec 2022, 47, 126–137
B.M. ter Ellen , J Niewold, A Flikweert, AC. Muller Kobold, P Heeringa, M van Meurs, J.M. Smit, P.H.J. van der Voort, I.A. Rodenhuis-Zybert, J. Moser.
Frontiers in Immunology, June 2022; doi: 10.3389/fimmu.2022.879033.
Impaired pulmonary function, muscle strength and quality of life in critically ill COVID-19 survivors. A.W. Flikweert, T.C.D. Rettig, K.M. Kant, I.C.F. de Backer, S. van der Sar-van der Brugge, N.J.M. van der Meer, P.H.J. van der Voort, M.J.J.H. Grootenboers. Neth J Crit Care, January 2022; 30(1): 20 - 23.
Comparison of outcome and characteristics between 6343 COVID-19 patients and 2256 other community-acquired viral pneumonia patients admitted to Dutch ICUs. S. Brinkman, F. Termorshuizen, D.A. Dongelmans, F. Bakhshi-Raiez, M.S. Arbous, D.W. de Lange, N.F. de Keizer, the Dutch COVID-19 Research Consortium. Journal of Critical Care 68 (2022) 76–82.
Mild Coronavirus Disease 2019 (COVID-19) Is Marked by Systemic Oxidative Stress: A Pilot Study. Larissa E. van Eijk, Adriana Tami, Jan-Luuk Hillebrands, Wilfred F. A. den Dunnen, Martin H. de Borst, Peter H. J. van der Voort, Marian L. C. Bulthuis, Alida C. M. Veloo, Karin I. Wold, María F. Vincenti González, Bernardina T. F. van der Gun, Harry van Goor, Arno R. Bourgonje. Antioxidants 2021, 10, 2022. https://doi.org/10.3390/antiox10122022
MOXIDECTIN AND IVERMECTIN INHIBIT SARS-COV-2 REPLICATION IN VERO E6 CELLS BUT NOT IN HUMAN PRIMARY AIRWAY EPITHELIUM CELLS. Dinesh Kumar N, Ter Ellen BM, Bouma EM, Troost B, van de Pol DPI, van der Ende-Metselaar HH, van Gosliga D, Apperloo L, Carpaij OA, van den Berge M, Nawijn MC, Stienstra Y, Rodenhuis-Zybert IA, Smit JM. Antimicrob Agents Chemother. 2021 Oct 11:AAC0154321. doi: 10.1128/AAC.01543-21.
Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts. Bos LDJ, Sjoding M, Sinha P, Bhavani SV, Lyons PG, Bewley AF, Botta M, Tsonas AM, Serpa Neto A, Schultz MJ, Dickson RP, Paulus F; PRoVENT-COVID collaborative group. Lancet Respir Med. 2021 Oct 12:S2213-2600(21)00365-9. doi: 10.1016/S2213-2600(21)00365-9.
Do-not-intubate status and COVID-19 mortality in patients admitted to Dutch non-ICU wards. van der Veer T, van der Sar-van der Brugge S, Paats MS, van Nood E, de Backer IC, Aerts JGJV, van der Eerden MM. Eur J Clin Microbiol Infect Dis. 2021 Oct;40(10):2207-2209. doi: 10.1007/s10096-021-04223-4.
Aspergillus test profiles and mortality in critically-ill COVID-19 patients. Ergün M, Brüggemann RJM, Alanio A, Dellière S, van Arkel A, Bentvelsen RG, Rijpstra T, van der Sar-van der Brugge S, Lagrou K, Janssen NAF, Buil JB, van Dijk K, Melchers WJG, Reijers MHE, Schouten JA, Wauters J, Cordey A, Soni S, White PL, van de Veerdonk FL, Verweij PE. J Clin Microbiol. 2021 Sep 8:JCM0122921. doi: 10.1128/JCM.01229-21.
DAMPening COVID-19 Severity by Attenuating Danger Signals. Silva-Lagos LA, Pillay J, van Meurs M, Smink A, van der Voort PHJ, de Vos P. Front Immunol. 2021 Aug 12;12:720192. doi: 10.3389/fimmu.2021.720192.
Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients. Kooistra EJ, Brinkman S, van der Voort PHJ, de Keizer NF, Dongelmans DA, Kox M, Pickkers P. Crit Care Med. 2021 Jul 16. doi: 10.1097/CCM.0000000000005216.
Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells. Ter Ellen BM, Dinesh Kumar N, Bouma EM, Troost B, van de Pol DPI, van der Ende-Metselaar HH, Apperloo L, van Gosliga D, van den Berge M, Nawijn MC, van der Voort PHJ, Moser J, Rodenhuis-Zybert IA, Smit JM. Viruses. 2021 Jul 10;13(7):1335. doi: 10.3390/v13071335.
Association of intensity of ventilation with 28-day mortality in COVID-19 patients with acute respiratory failure: insights from the PRoVENT-COVID study. Schuijt MTU, Schultz MJ, Paulus F, Serpa Neto A; PRoVENT–COVID Collaborative Group. Crit Care. 2021 Aug 6;25(1):283. doi: 10.1186/s13054-021-03710-6.
Six-Month Outcomes in COVID-19 ICU Patients and Their Family Members: A Prospective Cohort Study. van Veenendaal N, van der Meulen IC, Onrust M, Paans W, Dieperink W, van der Voort PHJ. Healthcare (Basel). 2021 Jul 8;9(7):865. doi: 10.3390/healthcare9070865.
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study. ISARIC Clinical Characterisation Group. Infection. 2021 Oct;49(5):889-905. doi: 10.1007/s15010-021-01599-5.
Comparison of renal histopathology and gene expression profiles between severe COVID-19 and bacterial sepsis in critically ill patients. Volbeda M, Jou-Valencia D, van den Heuvel MC, Knoester M, Zwiers PJ, Pillay J, Berger SP, van der Voort PHJ, Zijlstra JG, van Meurs M, Moser J. Crit Care. 2021 Jun 10;25(1):202. doi: 10.1186/s13054-021-03631-4.
Viral load dynamics in intubated patients with COVID-19 admitted to the intensive care unit. Boef AGC, van Wezel EM, Gard L, Netkova K, Lokate M, van der Voort PHJ, Niesters HGM, Van Leer Buter C. J Crit Care. 2021 Aug;64:219-225. doi: 10.1016/j.jcrc.2021.04.010.
Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS. Morales-Quinteros L, Neto AS, Artigas A, Blanch L, Botta M, Kaufman DA, Schultz MJ, Tsonas AM, Paulus F, Bos LD; PRoVENT-COVID Study Group. Crit Care. 2021 May 17;25(1):171. doi: 10.1186/s13054-021-03570-0.
Associations of Body Mass Index with Ventilation Management and Clinical Outcomes in Invasively Ventilated Patients with ARDS Related to COVID-19-Insights from the PRoVENT-COVID Study. Schavemaker R, Schultz MJ, Lagrand WK, van Slobbe-Bijlsma ER, Serpa Neto A, Paulus F; The PRoVENT-Covid Collaborative Group. J Clin Med. 2021 Mar 11;10(6):1176. doi: 10.3390/jcm10061176.
N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 2019. Bourgonje AR, Offringa AK, van Eijk LE, Abdulle AE, Hillebrands JL, van der Voort PHJ, van Goor H, van Hezik EJ. Antioxid Redox Signal. 2021 Nov 10;35(14):1207-1225. doi: 10.1089/ars.2020.8247.
COVID-19: immunopathology, pathophysiological mechanisms, and treatment options. van Eijk LE, Binkhorst M, Bourgonje AR, Offringa AK, Mulder DJ, Bos EM, Kolundzic N, Abdulle AE, van der Voort PH, Olde Rikkert MG, van der Hoeven JG, den Dunnen WF, Hillebrands JL, van Goor H. J Pathol. 2021 Jul;254(4):307-331. doi: 10.1002/path.5642.
Post-Mortem Diagnostics in COVID-19 AKI, More Often but Timely. Zijlstra JG, van Meurs M, Moser J. J Am Soc Nephrol. 2021 Jan;32(1):255. doi: 10.1681/ASN.2020091263.
Pulmonary function and health-related quality of life after COVID-19 pneumonia. van der Sar-van der Brugge S, Talman S, Boonman-de Winter L, de Mol M, Hoefman E, van Etten RW, De Backer IC.Respir Med. 2021 Jan;176:106272. doi: 10.1016/j.rmed.2020.106272.
A novel haemocytometric COVID-19 prognostic score developed and validated in an observational multicentre European hospital-based study. Linssen J, Ermens A, Berrevoets M, Seghezzi M, Previtali G, van der Sar-van der Brugge S, Russcher H, Verbon A, Gillis J, Riedl J, de Jongh E, Saker J, Münster M, Munnix IC, Dofferhof A, Scharnhorst V, Ammerlaan H, Deiteren K, Bakker SJ, Van Pelt LJ, Kluiters-de Hingh Y, Leers MP, van der Ven AJ. Elife. 2020 Nov 26;9:e63195. doi: 10.7554/eLife.63195.
Poor outcome of SARS-CoV-2 infection in patients with severe asthma on biologic therapy. Eger K, Hashimoto S, Braunstahl GJ, Brinke AT, Patberg KW, Beukert A, Smeenk F, van der Sar-van der Brugge S, Weersink EJM, Bel EH.Respir Med. 2020 Dec 24;177:106287. doi: 10.1016/j.rmed.2020.106287.
Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study. Botta M, Tsonas AM, Pillay J, Boers LS, Algera AG, Bos LDJ, Dongelmans DA, Hollmann MW, Horn J, Vlaar APJ, Schultz MJ, Neto AS, Paulus F; PRoVENT-COVID Collaborative Group. Lancet Respir Med. 2021 Feb;9(2):139-148. doi: 10.1016/S2213-2600(20)30459-8.
Late histopathologic characteristics of critically ill COVID-19 patients: Different phenotypes without evidence of invasive aspergillosis, a case series. Flikweert AW, Grootenboers MJJH, Yick DCY, du Mée AWF, van der Meer NJM, Rettig TCD, Kant MKM. J Crit Care. 2020 Oct;59:149-155. doi: 10.1016/j.jcrc.2020.07.002.
A Method to Improve Continuous Renal Replacement Therapy Circuit Survival Time in Critically Ill Coronavirus Disease 2019 Patients With Acute Kidney Injury. Volbeda M, Londema M, van Meurs M, Stegeman CA, Gansevoort RT, Berger SP, van der Voort PHJ, Franssen CFM. Crit Care Explor. 2020 Oct 15;2(10):e0258. doi: 10.1097/CCE.0000000000000258.
Rotational thromboelastometry to assess hypercoagulability in COVID-19 patients. van Veenendaal N, Scheeren TWL, Meijer K, van der Voort PHJ. Thromb Res. 2020 Dec;196:379-381. doi: 10.1016/j.thromres.2020.08.046.
Kidney Infarction in Patients With COVID-19. Post A, den Deurwaarder ESG, Bakker SJL, de Haas RJ, van Meurs M, Gansevoort RT, Berger SP. Am J Kidney Dis. 2020 Sep;76(3):431-435. doi: 10.1053/j.ajkd.2020.05.004.
Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissue. van der Voort PHJ, Moser J, Zandstra DF, Muller Kobold AC, Knoester M, Calkhoven CF, Hamming I, van Meurs M. Heliyon. 2020 Aug;6(8):e04696. doi: 10.1016/j.heliyon.2020.e04696.
In-hospital treatment of COVID-19 patients. de Wee EM, van der Sar-van der Brugge S, Grootenboers M, Bentvelsen RG, Kant KM, van der Leest CH.Ned Tijdschr Geneeskd. 2020 Jul 1;164:D4965.
Paediatric and adult critical care medicine: joining forces against Covid-19. Kneyber MCJ, Engels B, van der Voort PHJ. Crit Care. 2020 Jun 16;24(1):350. doi: 10.1186/s13054-020-03074-3.
Angiotensin-converting enzyme 2 (ACE2), SARS-CoV-2 and the pathophysiology of coronavirus disease 2019 (COVID-19). Bourgonje AR, Abdulle AE, Timens W, Hillebrands JL, Navis GJ, Gordijn SJ, Bolling MC, Dijkstra G, Voors AA, Osterhaus AD, van der Voort PH, Mulder DJ, van Goor H.J Pathol. 2020 Jul;251(3):228-248. doi: 10.1002/path.5471.